Psychosocial factors at work and in every day life are associated with irritable bowel syndrome
Psychosocial factors at work and in every day life are associated with irritable bowel syndrome
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DOI：
10.1007/s10654-007-9133-2
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发表时间：
2007-07-01
影响因子：
13.6
通讯作者：
Akerlind, Ingemar
中科院分区：
文献类型：
--
作者：
Faresjo, Ashild;Grodzinsky, Ewa;Akerlind, Ingemar
肠易激综合征（IBS）的病因往往是复杂的和多因素的，仍然缺乏了解如何不同的心理社会因素与综合征。我们的目的是研究在初级保健中诊断为IBS的患者中心理社会和行为因素的发生。该研究采用流行病学人群为基础的病例对照设计，将347例IBS病例与1041例年龄和性别匹配的普通人群对照进行比较。一项针对病例和对照的调查基于经验证的问题，询问情绪状态、工作压力、IBS家族史、睡眠习惯以及教育、营养和锻炼习惯和药物。在多变量分析中，发现IBS与缺乏对工作计划的影响、IBS家族史、焦虑和睡眠障碍之间存在独立关联。与女性IBS诊断相关的重要因素是焦虑、IBS家族史和工作中缺乏共同决定。对于男性，只有缺乏对工作节奏和IBS家族史的影响仍然与IBS诊断独立相关。IBS复杂危险因素的因果关系值得进一步研究。这项研究表明，应该特别关注调查的心理社会工作条件及其协会IBS。
The etiology of irritable bowel syndrome (IBS) tends to be complex and multi-factorial and there is still a lack of understanding of how different psychosocial factors are associated with the syndrome. Our aim was to examine the occurrence of psychosocial and behavioural factors among patients diagnosed with IBS in primary care. The study had an epidemiological population-based case-control design comparing 347 IBS cases to 1041 age and sex matched controls from the general population. A survey was directed to cases and controls based on validated questions asking for mood status, job strain, family history of IBS, and sleeping habits as well as education, nutritional and exercise habits and medication. In multivariate analyses, independent associations were found between IBS and lack of influence on work planning, a family history of IBS, anxiety, and sleeping disturbances. Important factors associated with IBS diagnosis among females were anxiety as well as family history of IBS and lack of co-determination at work. For males, only lack of influence on working pace and family history of IBS remained independently associated with an IBS diagnosis. The causal associations of the complex risk factor panorama for IBS warrants further study. This study indicates that there should be a special focus on investigating the psychosocial working conditions and their associations to IBS.