Prospective randomized trial comparing EUS and EGD for transmural drainage of pancreatic pseudocysts (with videos)

Prospective randomized trial comparing EUS and EGD for transmural drainage of pancreatic pseudocysts (with videos)
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DOI:
10.1016/j.gie.2008.04.028
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发表时间:
2008-12-01
影响因子:
7.7
通讯作者:
Wilcox, C. Mel
Wilcox, C. Mel
中科院分区:
医学1区
文献类型:
--
作者:
Varadarajulu, Shyam;Christein, John D.;Wilcox, C. Mel

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背景:虽然先前的研究评估了EUS和EGD在胰腺假性囊肿引流中的作用,但没有随机试验比较这两种方式的技术结果。目的:比较EUS与EGD在胰腺假性囊肿经壁引流术中的技术成功率。研究设计:前瞻性随机试验。环境:三级转诊中心。患者:有胰腺炎病史和症状性胰腺假性囊肿,尺寸大于4cm,经内镜下经壁引流的患者。排除胰腺脓肿或坏死患者。主要结果测量:技术成功被定义为通过放置跨壁支架进入和排出假性囊肿的能力。在24小时和第30天评估并发症。治疗成功的定义是假性囊肿完全消退或缩小到
Background: Although prior studies evaluated the role of EUS and EGD for drainage of pancreatic pseudocysts, there are no randomized trials that compared the technical Outcomes between both modalities.Objective: To compare the rate of technical Success between EUS and EGD for transmural drainage of pancreatic pseudocysts.Study design: A prospective randomized trial. Setting: A tertiary-referral center.Patients: Those with a history of pancreatitis and symptomatic pancreatic pseudocysts that measured greater than 4 cm in size who were referred for endoscopic transmural drainage. Patients with pancreatic abscess or necrosis were excluded.Main Outcome Measurements: Technical success was defined as the ability to access and drain a pseudocyst by placement of transmural stents. Complications were assessed at 24 hours and at day 30. Treatment success was defined as the complete resolution or decrease in size of the pseudocyst to