Enhanced internalization of ricin in nigericin-pretreated Chinese hamster ovary cells.

Enhanced internalization of ricin in nigericin-pretreated Chinese hamster ovary cells.
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经尼日利亚霉素预处理的中国仓鼠卵巢细胞中蓖麻毒素的内化增强。

DOI:
10.1128/mcb.1.6.560-567.1981
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发表时间:
1981
影响因子:
5.3
通讯作者:
Wu,HC
Wu,HC
中科院分区:
生物学2区
文献类型:
--
作者:
Ray,B;Wu,HC

文献摘要

相似文献

Biochemical and electron microscopic autoradiographic studies with [125I]ricin have revealed that nigericin-pretreated Chinese hamster ovary cells are more efficient than untreated cells in the internalization of the toxin into the cells. These results suggest that the enhanced rate of internalization of ricin in nigericin-pretreated cells may account for the enhancement of cytotoxicity of ricin in Chinese hamster ovary cells by nigericin.