(-)-Amarbellisine, a lycorine-type alkaloid from Amaryllis belladonna L. growing in Egypt
(-)-Amarbellisine, a lycorine-type alkaloid from Amaryllis belladonna L. growing in Egypt
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DOI：
10.1016/j.phytochem.2004.03.020
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发表时间：
2004-07-01
期刊：
影响因子：
3.8
通讯作者：
Motta, A
中科院分区：
文献类型：
--
作者：
Evidente, A;Andolfi, A;Motta, A
从埃及石蒜（Amaryllis belladonna L.）以及公知的生物碱（-）-石蒜碱、（-）-pancracine、（+）-vittatine、（+）-11-羟基vittatine和（+）-马槟榔碱。该生物碱为2-甲氧基-3a，4，5，7，11 b，11 c-六氢-1H-[1，3]间二氧杂环戊烯并[4，5-j]吡咯并[3，2，1-de]同时，利用高效薄层色谱技术，对两个不同生育期的菲啶醇相对含量和总含量进行了比较研究增长最后，对分离的生物碱进行了抑菌活性测定。(C)2004爱思唯尔有限公司保留所有权利。
A new lycorine-type alkaloid, named (-)-amarbellisine, was isolated from the bulbs of Egyptian Amaryllis belladonna L. together with the well known alkaloids (-)-lycorine, (-)-pancracine, (+)-vittatine, (+)-11-hydroxyvittatine, and (+)-hippeastrine. The new alkaloid, containing the pyrrolo[de]phenanthridine ring system, was essentially characterised by spectroscopic and optical methods, and proved to be the 2-methoxy-3a,4,5,7,11b,11c-hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridinol.By using HPTLC technique we also carried out a comparative study of the relative and total alkaloidal content at two different stages of plant growth. Finally, the antimicrobial activity of the isolated alkaloids was assayed. (C) 2004 Elsevier Ltd. All rights reserved.