The inactivation by fluorodinitrobenzene of glucose transport across the human erythrocyte membrane. The effect of glucose inside or outside the cell.

The inactivation by fluorodinitrobenzene of glucose transport across the human erythrocyte membrane. The effect of glucose inside or outside the cell.
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氟二硝基苯使葡萄糖穿过人红细胞膜的转运失活。

DOI:
10.1016/0005-2736(73)90107-7
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发表时间:
1973
期刊:
Biochimica et biophysica acta
影响因子:
--
通讯作者:
P. Edwards
P. Edwards
中科院分区:
--
文献类型:
--
作者:
P. Edwards

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氟二硝基苯对人红细胞中葡萄糖转运的失活在细胞外被120 mM葡萄糖加速,但在细胞内被120 mM葡萄糖延迟至少50%。这表明,当细胞内有葡萄糖时,转运系统主要处于一种构象,而当细胞外有葡萄糖时,转运系统主要处于另一种构象。
The inactivation of glucose transport in human red cells by fluorodinitrobenzene is accelerated by 120 mM glucose outside the cell but retarded at least 50% by 120 mM glucose inside the cell. This suggests that the transport system is predominantly in one conformation when there is glucose inside the cell, and in another conformation when there is glucose outside the cell.