Cancer stem cells: Implications for cancer treatment and prevention
Cancer stem cells: Implications for cancer treatment and prevention
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DOI：
10.1097/ppo.0b013e318156da4e
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发表时间：
2007-09-01
期刊：
影响因子：
2.2
通讯作者：
Wicha, Max S.
中科院分区：
文献类型：
--
作者：
Kakarala, Madhuri;Wicha, Max S.
癌症是美国第二大最常见的死亡原因，在2004年导致了55万人死亡。癌症研究人员在了解癌症的生物学起源、易患癌症的基因变化以及致癌过程本身所涉及的信号通路方面取得了快速进展。这些见解为现在和未来治疗癌症的尝试提供了方向。癌症干细胞生物学领域的发展是这些进步中最令人兴奋的一个。
Cancer is the second most common cause of mortality in the United States and resulted in >550,000 deaths in 2004. Cancer researchers have been making rapid advances in understanding the biologic origin of cancer, the genetic changes that predispose to it, and the signaling pathways involved in the carcinogenesis process itself. Such insights lend direction to present and future attempts to treat cancer. The developing field of cancer stem cell biology is one of the most exciting of these advances.