Hyperintense Plaque on Intracranial Vessel Wall Magnetic Resonance Imaging as a Predictor of Artery-to-Artery Embolic Infarction
Hyperintense Plaque on Intracranial Vessel Wall Magnetic Resonance Imaging as a Predictor of Artery-to-Artery Embolic Infarction
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颅内血管壁磁共振成像高信号斑块作为动脉间栓塞性梗塞的预测因子
DOI：
10.1161/strokeaha.117.020046
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发表时间：
2018-04-01
期刊：
影响因子：
8.3
通讯作者：
Fan, Zhaoyang
中科院分区：
文献类型：
--
作者：
Wu, Fang;Song, Haiqing;Fan, Zhaoyang
背景和目的-本研究的目的是通过全脑高分辨率磁共振成像研究动脉-动脉（A-to-A）栓塞性梗死患者的动脉粥样硬化斑块特征。（平均年龄：54.7 ± 12.1岁;前瞻性入选了59例因颅内动脉粥样硬化性疾病在大脑中动脉区域近期发生卒中的男性患者。通过使用三维T1加权血管壁磁共振成像技术（称为反转恢复准备采样完美技术）以及使用不同翻转角的应用优化对比度，对所有患者进行了全脑高分辨率磁共振成像。演变。根据弥散加权成像结果将患者分为A至A栓塞性梗死组和非A至A栓塞性梗死组。结果-共分析了74个颅内动脉粥样硬化斑块（A-to-A栓塞组36个，非A-to-A栓塞组38个）。高信号斑块（HIPs）在A-to-A栓塞组中更常见（75.0%vs21.1%; P
Background and Purpose-The aim of the present study was to investigate atherosclerotic plaque characteristics in patients with artery-to-artery (A-to-A) embolic infarction by whole-brain high-resolution magnetic resonance imaging.Methods-Seventy-four patients (mean age, 54.7 +/- 12.1 years; 59 men) with recent stroke in the territory of middle cerebral artery because of intracranial atherosclerotic disease were prospectively enrolled. Whole-brain high-resolution magnetic resonance imaging was performed in all the patients both precontrast and postcontrast administration by using a 3-dimensional T1-weighted vessel wall magnetic resonance imaging technique known as inversion-recovery prepared sampling perfection with application-optimized contrast using different flip angle evolutions. Patients were divided into A-to-A embolic infarction and non-A-to-A embolic infarction groups based on diffusion-weighted imaging findings. The characteristics of the intracranial atherosclerotic plaques were compared between groups.Results-A total of 74 intracranial atherosclerotic plaques were analyzed (36 in A-to-A embolism group and 38 in non-Ato-A embolism group). Hyperintense plaques (HIPs) were more frequently observed in A-to-A embolism group (75.0% versus 21.1%; P