EPIDEMIOLOGIC CORRELATES OF PRETERM PREMATURE RUPTURE OF MEMBRANES

EPIDEMIOLOGIC CORRELATES OF PRETERM PREMATURE RUPTURE OF MEMBRANES
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DOI:
10.1016/0020-7292(94)90454-5
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发表时间:
1994-10-01
影响因子:
3.8
通讯作者:
BALTARO, F
BALTARO, F
中科院分区:
医学4区
文献类型:
--
作者:
SPINILLO, A;NICOLA, S;BALTARO, F

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目的:探讨早产胎膜早破(FROM)的临床危险因素。方法:我们对 138 名妊娠 24 至 35 周之间的 FROM 患者和 267 名对照受试者进行了病例对照研究。结果:在逐步多元逻辑回归模型中,病例群体更有可能属于低社会阶层。 FROM 的其他危险因素包括怀孕期间吸烟、妊娠第一或第二至第三个月出血、宫颈机能不全以及妊娠期间有记录的宫颈阴道感染。妊娠早期出血和妊娠期间记录的宫颈阴道感染与未产妇和多产妇女的早产有关。结论:很少有潜在可补救的危险因素与早产 FROM 的发生相关。
Objective: To study the clinical risk factors for preterm premature rupture of membranes (FROM). Method: We conducted a case-control study of 138 patients with FROM between 24 and 35 weeks' gestation and 267 control subjects. Results: In stepwise multiple logistic regression models, the population of cases was more likely to be of low social class. Other risk factors for FROM were smoking in pregnancy, Ist or 2nd-3rd trimester hemorrhages, cervical incompetence and a documented cervico-vaginal infection during index pregnancy. First trimester hemorrhage and a documented cervico-vaginal infection during index pregnancy were associated with preterm FROM both in nulliparous and in multiparous women. Conclusion: Few potentially remediable risk factors are associated with the occurrence of preterm FROM.