The international glycan repository GlyTouCan version 3.0.

The international glycan repository GlyTouCan version 3.0.
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DOI:
10.1093/nar/gkaa947
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发表时间:
2021-01-08
影响因子:
14.9
通讯作者:
Aoki-Kinoshita KF
Aoki-Kinoshita KF
中科院分区:
生物学2区
文献类型:
--
作者:
Fujita A;Aoki NP;Shinmachi D;Matsubara M;Tsuchiya S;Shiota M;Ono T;Yamada I;Aoki-Kinoshita KF

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聚糖在信号转导和细胞间通讯中起着重要作用,它们被凝集素、病毒和细菌识别,在许多生物过程中发挥着各种作用。然而,没有系统来组织文献中过多的聚糖相关数据。因此,GlyTouCan(glytoucan.org)被开发为国际聚糖库,允许研究人员为聚糖分配登录号。这也有助于跨各种数据库整合聚糖数据。GlyTouCan将登录号分配给定义为单糖组的聚糖,这些单糖组可能会或可能不会用连接信息进行表征。GlyTouCan的开发旨在能够识别聚糖中的任何模糊程度,并为每个聚糖唯一分配登录号,而无论输入文本格式如何。在这篇手稿中,我们描述了GlyTouCan 3.0版本的最新更新,它的使用方法以及未来的发展计划。
Glycans serve important roles in signaling events and cell-cell communication, and they are recognized by lectins, viruses and bacteria, playing a variety of roles in many biological processes. However, there was no system to organize the plethora of glycan-related data in the literature. Thus GlyTouCan (https://glytoucan.org) was developed as the international glycan repository, allowing researchers to assign accession numbers to glycans. This also aided in the integration of glycan data across various databases. GlyTouCan assigns accession numbers to glycans which are defined as sets of monosaccharides, which may or may not be characterized with linkage information. GlyTouCan was developed to be able to recognize any level of ambiguity in glycans and uniquely assign accession numbers to each of them, regardless of the input text format. In this manuscript, we describe the latest update to GlyTouCan in version 3.0, its usage, and plans for future development.
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