TOMOTHERAPY - A NEW CONCEPT FOR THE DELIVERY OF DYNAMIC CONFORMAL RADIOTHERAPY
TOMOTHERAPY - A NEW CONCEPT FOR THE DELIVERY OF DYNAMIC CONFORMAL RADIOTHERAPY
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DOI：
10.1118/1.596958
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发表时间：
1993-11-01
期刊：
影响因子：
3.8
通讯作者：
KINSELLA, T
中科院分区：
文献类型：
--
作者：
MACKIE, TR;HOLMES, T;KINSELLA, T
断层治疗，字面意思是“切片治疗”，是一种用强度调制的辐射带进行放射治疗的建议。所提出的方法采用线性加速器或另一种辐射发射装置，其将安装在环形台架上，如CT扫描仪。患者将在机架旋转的同时移动通过机架的孔。强度调制将通过跨狭缝开口打开和关闭的时间调制的多个独立叶片来执行。在任何给定的时间，任何叶片将（1）关闭，覆盖狭缝的一部分，（2）打开，允许辐射通过，或（3）在这些状态之间变化。这种方法将导致高度适形辐射的递送。总体治疗时间应与当前的治疗时间相当。环形机架将便于在治疗单元上安装用于射束验证的窄多段兆伏检测器系统和CT扫描仪。这样的治疗单元可以成为一个强大的工具，治疗计划，适形治疗，并使用断层图像验证。这种治疗交付的物理性能进行了评估，并证明了基本的设计规范。
Tomotherapy, literally ''slice therapy,'' is a proposal for the delivery of radiation therapy with intensity-modulated strips of radiation. The proposed method employs a linear accelerator, or another radiation-emitting device, which would be mounted on a ring gantry like a CT scanner. The patient would move through the bore of the gantry simultaneously with gantry rotation. The intensity modulation would be performed by temporally modulated multiple independent leaves that open and close across the slit opening. At any given time, any leaf would be (1) closed, covering a portion of the slit, (2) open, allowing radiation through, or (3) changing between these states. This method would result in the delivery of highly conformal radiation. Overall treatment times should be comparable with contemporary treatment delivery times. The ring gantry would make it convenient to mount a narrow multisegmented megavoltage detector system for beam verification and a CT scanner on the treatment unit. Such a treatment unit could become a powerful tool for treatment planning, conformal treatment, and verification using tomographic images. The physical properties of this treatment delivery are evaluated and the fundamental design specifications are justified.