Cardiac fat navigator-gated steady-state free precession 3D magnetic resonance angiography of coronary arteries

Cardiac fat navigator-gated steady-state free precession 3D magnetic resonance angiography of coronary arteries
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DOI:
10.1002/mrm.20938
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发表时间:
2006-07-01
影响因子:
3.3
通讯作者:
Wang, Yi
Wang, Yi
中科院分区:
医学3区
文献类型:
--
作者:
Nguyen, Thanh D.;Spincemaille, Pascal;Wang, Yi

文献摘要

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运动伪影和缺乏对心脏运动的准确检测给高分辨率心脏 MRI 带来了重大挑战。最近,提出了一种多维心脏脂肪导航器来提供大量心脏运动的快速和直接测量。本研究的目的是证明在平衡稳态自由进动 (SSFP) 自由呼吸 3D 冠状动脉 MRA (CMRA) 中使用心脏脂肪导航仪的可行性。心脏脂肪导航器回波经过优化,可提供运动监测和心外膜脂肪抑制。 SSFP CMRA 所需的稳态磁化准备通过比较三种准备方案进行了优化:α/2、具有 20 个 RF 脉冲的线性斜坡 (20LR) 和具有 6 个 RF 脉冲的 Kaiser 斜坡 (6KR)。目前的初步人体研究表明,对于自由呼吸 SSFP 3D CMRA (N = 11),6KR 制剂比 alpha/2 (P < 0.0025) 和 20LR 制剂 (P < 0.025) 提供更好的图像质量。
Motion artifacts and the lack of accurate detection of cardiac motion present a major challenge for high-resolution cardiac MRI. Recently a multidimensional cardiac fat navigator was proposed to provide a fast and direct measurement of bulk cardiac motion. The objective of this study was to demonstrate the feasibility of employing the cardiac fat navigator in balanced steady-state free precession (SSFP) free-breathing 3D coronary MRA (CMRA). The cardiac fat navigator echo is optimized to provide both motion monitoring and epicardial fat suppression. Steady-state magnetization preparation, which is needed for SSFP CMRA, is optimized by comparing three preparation schemes: alpha/2, linear ramp with 20 RF pulses (20LR), and Kaiser ramp with six RF pulses (6KR). The present preliminary human study shows that the 6KR preparation provides better image quality than both the alpha/2 (P < 0.0025) and the 20LR preparations (P < 0.025) for free-breathing SSFP 3D CMRA (N = 11).