Molecular recognition of organic acids and anions — Receptor models for carboxylates, amino acids, and nucleotides
Molecular recognition of organic acids and anions — Receptor models for carboxylates, amino acids, and nucleotides
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有机酸和阴离子的分子识别 - 羧酸盐、氨基酸和核苷酸的受体模型
DOI：
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发表时间：
1995
期刊：
影响因子：
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通讯作者：
J. Mendoza
中科院分区：
文献类型：
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作者：
C. Seel;A. Galán;J. Mendoza
合成分子识别和超分子化学本身的根源在于金属离子的有机配体的研究，这一领域的研究是压倒性的。然而，长期以来，即使原始策略具有可比性，人们对阴离子络合的兴趣也要少得多，直到最近几年，所取得的进展才越来越有活力。特别是生物相关物种的受体分子，如氨基酸和核苷酸，是主要的研究目标，尤其是因为它们在医学上的潜在应用。在这篇文章中，将总结到目前为止在这里取得的进展，细心的读者可能会注意到，大多数引用的主要文献都不到五年的历史。重点没有放在结构特征或合成策略上，而是放在新的宿主分子产生的影响和它们可能具有的功能上。
The roots of synthetic molecular recognition and supramolecular chemistry itself lie in the investigation of organic ligands for metal cations, and the amount of research done in this field is overwhelming. For a long time, however, far less interest has been focussed on the complexation of anions even if the primal strategies were comparable, and only in recent years have the advances made been increasingly dynamic. In particular receptor molecules for biorelevant species such as amino acids and nucleotides are primary research targets, not least for their potential applications in medicine. In this article the developments which have been made here so far will be summarized and the attentive reader might notice that most of the primary literature cited is less than five years old. The emphasis has not been laid upon structural characteristics or synthetic strategies but rather on the effects the new host molecules give rise to and the functions they may have.