Trends in antenatal HIV prevalence in urban Uganda associated with uptake of preventive sexual behaviour
Trends in antenatal HIV prevalence in urban Uganda associated with uptake of preventive sexual behaviour
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DOI：
10.1136/sti.2005.017111
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发表时间：
2006-04-01
影响因子：
3.6
通讯作者：
Bessinger, R
中科院分区：
文献类型：
--
作者：
Kirungi, WL;Musinguzi, J;Bessinger, R
背景资料：乌干达的流行病学监测一直显示，自1990年代初以来，艾滋病毒流行率不断下降，特别是在年轻产前妇女中，这与保护性行为的增加有关。方法：审查哨点监测系统提供的产前艾滋病毒血清阳性率数据（1989 - 2002年）和全国人口与健康调查艾滋病单元（1989、1995和2000/2001年）的性行为指标数据。生物和行为指标的趋势assessed.Results：产前艾滋病毒血清阳性率在7个城市诊所达到高峰，1992年左右（15 - 30%），随后稳步下降，到2002年（5 - 12%），最显着的是15 - 19岁和20 - 24岁的妇女。与此同时，全国年轻人的初级和次级禁欲率也在上升。妇女初次性行为的平均年龄从1989年的16.5岁增加到2000年的17.3岁，男子从1995年的17.6岁增加到2000年的18.3岁。1995年至2000年期间，妇女的婚前性行为和多重伴侣关系有所减少。男性报告婚外性行为的情况没有显著变化。曾经使用避孕套的妇女和男子分别从1989年的1%和1995年的16%增加到2000年的16%和40%。在1995年和2000年之间，安全套的使用在最后的性行为与非经常性伙伴增加了35%至59%和20%至39%among men and women，respectively.Conclusion：在艾滋病毒的流行和发病率的趋势和增加在20世纪90年代的保护性行为之间的生态相关性，使一个令人信服的情况下，继续在乌干达的预防工作。
Background: Epidemiological surveillance in Uganda has consistently shown declining HIV prevalence particularly among young antenatal women since the early 1990s, correlated with increased uptake of protective sexual behaviour.Objective: To describe trends in sexual behaviour nationwide and antenatal HIV prevalence from urban sentinel sites in Uganda ( 1989 - 2002).Methods: Review of antenatal HIV seroprevalence data from the sentinel surveillance system ( 1989 - 2002) and data on sexual behavioural indicators from the AIDS module of the National Demographic and Health Surveys ( 1989, 1995 and 2000/01). Trends in biological and behavioural indicators assessed.Results: Antenatal HIV seroprevalence in seven urban clinics peaked around 1992 ( 15 - 30%) followed by a steady decline by 2002 ( 5 - 12%), most markedly among women aged 15 - 19 and 20 - 24 years. This coincided with increased primary and secondary abstinence among young people nationwide. Median age at sexual debut increased from 16.5 in 1989 to 17.3 in 2000 for women and from 17.6 in 1995 to 18.3 in 2000 for men. Premarital sex among women and multiple partnerships decreased between 1995 and 2000. There were no significant changes in reporting of extramarital sex among men. Ever use of condoms increased from 1% among women in 1989 and 16% among men in 1995 to 16% and 40% in 2000, respectively. Between 1995 and 2000, condom use at last sex with a non-regular partner increased from 35% to 59% and 20% to 39% among men and women, respectively.Conclusion: The ecological correlation between the trends in HIV prevalence and incidence and the increase in protective sexual behaviour during the 1990s makes a compelling case for continuing prevention efforts in Uganda.