Clinical spectrum and transmission characteristics of infection with Norwalk-like virus:: Findings from a large community outbreak in Sweden
Clinical spectrum and transmission characteristics of infection with Norwalk-like virus:: Findings from a large community outbreak in Sweden
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DOI：
10.1086/322608
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发表时间：
2001-09-01
影响因子：
11.8
通讯作者：
Giesecke, J
中科院分区：
文献类型：
--
作者：
Götz, H;Ekdahl, K;Giesecke, J
诺瓦克样病毒（NLV）在30个日托中心的儿童和工作人员中引起的大规模食源性暴发，为研究不同年龄组患者的症状学和发病率以及中心和家庭中的二次传播率提供了机会。对来自13个随机选择的中心的775名受试者进行回顾性队列研究。腹泻在成人中比在儿童中更常见（P=.001），而呕吐则相反（P=.003）。原发性发作率为27%（524例受试者中142例）：成人为54%，儿童为19% (P
A large foodborne outbreak caused by Norwalk-like virus (NLV) among children and staff at 30 day care centers provided an opportunity to study symptomatology and attack rates among patients in different age groups, as well as secondary transmission rates in centers and households. A retrospective cohort study of 775 subjects from 13 randomly chosen centers was performed. Diarrhea was more common in adults than in children (P=.001), whereas the reverse was noted with regard to vomiting (P=.003). The primary attack rate was 27% (142 of 524 subjects): 54% of adults versus 19% of children (P