E-Cigarette or Vaping Product Use-associated Lung Injury: Developing a Research Agenda An NIH Workshop Report
E-Cigarette or Vaping Product Use-associated Lung Injury: Developing a Research Agenda An NIH Workshop Report
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DOI：
10.1164/rccm.201912-2332ws
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发表时间：
2020-09-15
影响因子：
24.7
通讯作者：
Tarran, Robert
中科院分区：
文献类型：
--
作者：
Alexander, Laura E. Crotty;Ware, Lorraine B.;Tarran, Robert
NHLBI 于 2019 年 10 月 23 日召开了一个工作组，以确定电子烟或电子烟产品使用相关肺损伤 (EVALI) 方面最相关、最紧迫的研究重点和普遍挑战。多个学科的专家讨论了 EVALI 疫情的复杂性，确定了研究重点，并提出了最有效地解决其致病因素并改进该疾病的诊断、治疗和预防的策略。确定了许多研究重点，包括需要建立国家和国际 EVALI 患者登记册，以准确跟踪受影响的患者并评估结果。该小组得出的结论是，迫切需要来自 EVALI 受试者的生物样本来帮助确定 EVALI 发病机制，并且电子烟具有与吸烟不同的疾病风险，EVALI 的发生凸显了将电子烟研究扩展到吸烟相关疾病之外的重要性。
The NHLBI convened a working group on October 23, 2019, to identify the most relevant and urgent research priorities and prevailing challenges in e-cigarette or vaping product use-associated lung injury (EVALI). Experts across multiple disciplines discussed the complexities of the EVALI outbreak, identified research priorities, and recommended strategies to address most effectively its causal factors and improve diagnosis, treatment, and prevention of this disease. Many research priorities were identified, including the need to create national and international registries of patients with EVALI, to track accurately those affected and assess outcomes. The group concluded that biospecimens from subjects with EVALI are urgently needed to help define EVALI pathogenesis and that vaping has disease risks that are disparate from smoking, with the occurrence of EVALI highlighting the importance of broadening e-cigarette research beyond comparators to smoking-related diseases.