Modular design of profluorescent polymer sensors
Modular design of profluorescent polymer sensors
复制标题
DOI：
10.1039/c5py00120j
复制
发表时间：
2015-03
期刊：
影响因子：
--
通讯作者：
Emily M. Simpson;Z. Ristovski;S. Bottle;K. Fairfull‐Smith;J. Blinco
中科院分区：
文献类型：
--
作者：
Emily M. Simpson;Z. Ristovski;S. Bottle;K. Fairfull‐Smith;J. Blinco
一个简单的模块化策略的合成含氮氧化物的聚合物。在使用ATRP合成的聚合物主链上引入环氧化物作为侧基官能团，随后用叠氮化钠进行亲核开环，得到3-键半径内的羟基和叠氮化物官能团。正交耦合化学，然后允许独立的连接的荧光团和氮氧基团在紧密接近，产生一个profluorescent聚合物。这些材料作为荧光传感器的可行性的验证证明通过有效的荧光开关时观察到的材料暴露于模型还原剂或碳为中心的自由基源。
A simple modular strategy for the synthesis of profluorescent nitroxide containing polymers is described. The incorporation of an epoxide as a pendant functionality on a polymer backbone synthesized using ATRP and subsequent nucleophilic ring-opening with sodium azide gave hydroxyl and azide functionality within a 3-bond radius. Orthogonal coupling chemistry then allowed the independent attachment of fluorophore and nitroxide groups in close proximity, giving rise to a profluorescent polymer. Validation of the viability of these materials as fluorescent sensors is demonstrated through efficient fluorescence switch-on observed when the materials are exposed to a model reductant or carbon-centred radical source.