Focal ictal direct current shifts by a time constant of 2 seconds were clinically useful for resective epilepsy surgery
Focal ictal direct current shifts by a time constant of 2 seconds were clinically useful for resective epilepsy surgery
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时间常数为 2 秒的局灶性发作直流电偏移在临床上对癫痫切除手术有用
作者：
Masaki Izumi;Katsuya Kobayashi;S. Kajikawa;K. Kanazawa;Y. Takayama;K. Iijima;Masaki Iwasaki;Yoji Okahara;S. Mine;Y. Iwadate;Akio Ikeda
癫痫发作直流电移（icDCs）和癫痫发作高频振荡（icHFOs）作为癫痫手术预后较好的替代指标已被报道。国际发展中国家分为两类：快速发展和缓慢发展。icDCs的时间常数为10s (TC10s)；然而，许多研究所使用的是时间常数为2s （TC2s）的脑电图。本研究旨在评估TC2s是否能充分观察到icDCs；此外，研究了icDCs或icfos切除的核心区与手术结果、各类型icDCs的发生率以及各类型icDCs与病理的关系。
Ictal direct current shifts (icDCs) and ictal high‐frequency oscillations (icHFOs) have been reported as surrogate markers for better surgical outcomes in epilepsy surgery. icDCs have been classified into two types: rapid and slow development. icDCs have been investigated with a time constant of 10 s (TC10s); however, many institutes use electroencephalography with a time constant of 2 s (TC2s). This study aimed to evaluate whether icDCs can be observed adequately with TC2s; moreover, it examined the relationship between the resected core area of icDCs or icHFOs and surgical outcomes, occurrence rate of each type of icDCs, and relationship between each type of icDCs and pathology.