Manufacture by water/oil emulsification of porous agarose beads: Effect of processing conditions on mean particle size, size distribution and mechanical properties
Manufacture by water/oil emulsification of porous agarose beads: Effect of processing conditions on mean particle size, size distribution and mechanical properties
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DOI：
10.1016/j.cep.2005.03.005
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发表时间：
2005-10-01
影响因子：
4.3
通讯作者：
Pacek, AW
中科院分区：
文献类型：
--
作者：
Mu, Y;Lyddiatt, A;Pacek, AW
研究了在单一搅拌容器中采用乳化法制备多孔琼脂糖微珠的工艺条件对微珠平均粒径、粒径分布和机械性能的影响。已经发现，颗粒尺寸和平均能量耗散率之间的关系是类似的湍流和珠的机械性能取决于流体动力学条件在形成和施加到珠的负载。结果表明，在搅拌容器中制造多孔珠是在高剪切乳化剂中进行乳化的有吸引力的替代方案。(c)2005 Elsevier B.V.保留所有权利。
The effect of processing conditions on the mean size, size distributions and mechanical properties of porous agarose beads manufactured by an emulsification methodology conducted in a single stirred vessel has been investigated. It has been found that the relation between particle size and average energy dissipation rate is similar to one developed for turbulent flow and that the mechanical properties of the beads depend on hydrodynamic conditions at formation and the load applied to the beads. The results imply that manufacturing of porous beads in a stirred vessel is an attractive alternative to the emulsification carried out in high shear emulsifiers. (c) 2005 Elsevier B.V. All rights reserved.