Sourcing Photoreceptor-like Cells for Treating Vision Loss.

Sourcing Photoreceptor-like Cells for Treating Vision Loss.
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寻找光感受器样细胞治疗视力丧失。

DOI:
10.1056/nejmcibr2027602
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发表时间:
2020-11-05
影响因子:
158.5
通讯作者:
Apte, Rajendra S.
Apte, Rajendra S.
中科院分区:
医学1区
文献类型:
--
作者:
Apte, Rajendra S.

文献摘要

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视网膜光感受器细胞的丧失是视力丧失的关键事件。一种新的,尽管是试探性的,纠正感光细胞损失的策略涉及将成纤维细胞重编程为化学诱导的光感受器样细胞。
New Experimental Approach to Retinal DegenerationLoss of retinal photoreceptor cells is a critical event in loss of vision. A new, albeit tentative, strategy to rectify the loss of photoreceptor cells involves reprogramming fibroblasts into chemically induced photoreceptor-like cells.