ANTICIPATORY ACTIVITY RHYTHMS UNDER DAILY SCHEDULES OF WATER ACCESS IN THE RAT
ANTICIPATORY ACTIVITY RHYTHMS UNDER DAILY SCHEDULES OF WATER ACCESS IN THE RAT
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DOI：
10.1177/074873049200700206
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发表时间：
1992-06-01
影响因子：
3.5
通讯作者：
MISTLBERGER, RE
中科院分区：
文献类型：
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作者：
MISTLBERGER, RE
大鼠预期一个固定的每日喂养时间夹带其多振荡昼夜节律系统的组成部分。能够夹带这一组成部分的刺激的范围很少研究。以前的研究表明，限制水的访问是不是一个有效的夹带刺激，一般运动测量。本研究重新审视了这个问题，使用其他两个活动的措施：车轮运行和活动在食品-水交付箱。大鼠限制1小时的水，每天在中间的光和食物在12小时的黑暗时期没有表现出预期的这一事件在车轮运行措施，但一些大鼠确实表现出预期的交付箱活动措施。大鼠（bin活动测量）限制在1小时的水和1小时的食物分开的时间间隔为7，10，或12小时，在光照或黑暗中，表现出一致的预期的食物访问时间，但很少或没有预期的水访问时间。水的访问时间也没有维持食物预期的节奏在动物的食物-水的时间表被逆转。然而，剥夺水或食物和水72或90小时通常与特定的增加在通常的喂养和饮用时间的bin活动。水的获取，像食物一样，似乎提供了能够夹带预期昼夜节律机制的线索。这些事件之前的预期活动的类型和数量的差异可能反映了两种夹带线索的强度和/或饥饿和口渴促进的活动水平或特定行为策略的差异。
Rats anticipate a fixed daily feeding time by entrainment of a component of their multioscillatory circadian system. The range of stimuli capable of entraining this component is little studied. Previous studies suggest that restricted water access is not an effective entrainment stimulus, as measured by general locomotion. The present study re-examined the issue, using two other measures of activity: wheel running and activity at a food-water delivery bin. Rats restricted to 1 hr of water each day in the middle of the light and to food in the 12-hr dark period showed no anticipation of this event in the wheel-running measure, but some rats did show anticipation in the delivery bin activity measure. Rats (bin activity measure only) restricted to 1 hr of water and 1 hr of food separated by intervals of 7, 10, or 12 hr, in either the light or the dark, showed consistent anticipation of food access time but little or no anticipation of water access time. Water access time also did not sustain food anticipatory rhythms in animals whose food-water schedules were reversed. However, deprivation of water or of both food and water for 72 or 90 hr was usually associated with specific increases in bin activity at both the usual feeding and drinking times. Water access, like food, appears to provide cues capable of entraining an anticipatory circadian mechanism. Differences in the type and amount of anticipatory activity preceding these events may reflect differences in the strengths of the two entrainment cues and/or in the activity levels or specific behavioral strategies promoted by hunger and thirst.