Classical conditioning and conditioning-specific reflex modification of rabbit heart rate as a function of unconditioned stimulus location.
Classical conditioning and conditioning-specific reflex modification of rabbit heart rate as a function of unconditioned stimulus location.
复制标题
兔子心率的经典条件反射和条件特异性反射修正作为无条件刺激位置的函数。
DOI：
10.1037/a0024325
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发表时间：
2011
影响因子：
1.9
通讯作者：
Burhans,LaurenB
中科院分区：
文献类型：
--
作者：
Schreurs,BernardG;Smith-Bell,CarrieA;Burhans,LaurenB
心率调节被用作条件性恐惧的指标，对于理解焦虑和压力障碍，包括创伤后应激障碍（PTSD）很重要。PTSD的一个重要特征是患者将条件性恐惧从危险信号泛化为安全信号，特别是当两种信号具有重叠特征时。尚未确定的是，是否泛化发生在具有重叠特征的无条件刺激之间。在本实验中，心率条件反射和条件反射特异性修改的兔心率作为两个不同的非条件刺激位置的函数进行了检查。无论电刺激是在眼睛附近还是在背部，心率调节都发生在相同的终端水平。尽管在两个位置对电刺激的心率反应地形不同，但在眼睛附近和背部检测到条件反射特异性修改，并且似乎在位置之间泛化。有趣的是，在心率调节后，仅在背部检测到的条件反射修饰持续了一周。这种持续性可能是创伤后应激障碍的一些特征的模型。对类似于创伤的无条件刺激的无条件反应的过度概括也可能是这里建模的PTSD的一个重要方面。（PsycInfo数据库记录（c）2016阿帕，保留所有权利）
Heart rate conditioning is used as an index of conditioned fear and is important for understanding disorders of anxiety and stress, including post traumatic stress disorder (PTSD). One important feature of PTSD is that patients generalize conditioned fear from danger signals to safety signals especially when the two signals have overlapping features. What has not been determined is whether generalization occurs between unconditioned stimuli with overlapping features. In the current experiment, heart rate conditioning and conditioning-specific reflex modification of rabbit heart rate were examined as a function of two different unconditioned stimulus locations. Heart rate conditioning occurred at identical terminal levels whether electrical stimulation was presented near the eye or on the back. Despite different heart rate response topographies to electrical stimulation at the two locations, conditioning-specific reflex modification was detected near the eye and on the back and appeared to generalize between the locations. Interestingly, only conditioning-specific reflex modification detected on the back persisted for a week after heart rate conditioning. This persistence may be a model for some features of post traumatic stress disorder. Overgeneralization of unconditioned responses to unconditioned stimuli similar to the trauma may also be an important aspect of PTSD modeled here.(PsycINFO Database Record (c) 2016 APA, all rights reserved)