Creating connected representations of cortical gray matter for functional MRI visualization
Creating connected representations of cortical gray matter for functional MRI visualization
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DOI：
10.1109/42.650881
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发表时间：
1997-12-01
影响因子：
10.6
通讯作者：
Wandell, BA
中科院分区：
文献类型：
--
作者：
Teo, PC;Sapiro, G;Wandell, BA
我们描述了一种用于从磁共振成像(MRI)中分割灰质并为功能MRI可视化(FMRI)创建连接的皮质表示的系统。该方法利用大脑皮层的解剖学知识，并将结构约束融入分割中，首先，使用一种新的后验各向异性扩散技术分割MR体积中的白质和脑脊液(CSF)区域，然后，用户选择感兴趣的皮质白质成分，并通过检查空洞和手柄来验证其结构。在此之后，灰质的连接表示是通过从白质边界向外的受限生长创建的，因为连接性是计算出来的，分割可以被用作几种可视化灰质内皮质活动的空间模式的方法的输入，在我们的例子中，灰质的连接表示被用来创建皮质的平面化表示，然后，fMRI测量被覆盖在平面化表示上，产生单个图像内的体积数据的表示，该软件可免费向研究团体提供。
We describe a system that is being used to segment gray matter from magnetic resonance imaging (MRI) and to create connected cortical representations for functional MRI visualization (fMRI). The method exploits knowledge of the anatomy of the cortex and incorporates structural constraints into the segmentation, First, the white matter and cerebral spinal fluid (CSF) regions in the MR volume are segmented using a novel techniques of posterior anisotropic diffusion, Then, the user selects the cortical white matter component of interest, and its structure is verified by checking for cavities and handles. After this, a connected representation of the gray matter is created by a constrained growing-out from the white matter boundary, Because the connectivity is computed, the segmentation can be used as input to several methods of visualizing the spatial pattern of cortical activity within gray matter, In our case, the connected representation of gray matter is used to create a flattened representation of the cortex, Then, fMRI measurements are overlaid on the flattened representation, yielding a representation of the volumetric data within a single image, The software is freely available to the research community.