Failure of metallothionein to bind iron or act as an iron mobilizing agent.
Failure of metallothionein to bind iron or act as an iron mobilizing agent.
复制标题
金属硫蛋白未能结合铁或充当铁动员剂。
DOI：
10.1016/0304-4165(82)90278-1
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发表时间：
1982
期刊：
影响因子：
--
通讯作者：
Bates,GW
中科院分区：
文献类型：
--
作者：
Kojima,N;Young,CR;Bates,GW
有理由表明金属硫蛋白可能作为一种短暂的细胞内铁转运剂。从镉处理的动物中分离出兔肾金属硫蛋白，以诱导金属硫蛋白的合成。尝试通过几种反应途径形成铁-蛋白质复合物。没有证据表明有复杂的形成。金属硫蛋白也未能动员铁的幽灵兔网织红细胞特异性标记与59铁。
There are reasons to suggest metallothionein might act as a transient intracellular iron transport agent. Rabbit kidney metallothionein was isolated from animals treated with Cd in order to induce metallothionein synthesis. Attempts were made to form the iron-protein complex via several reaction routes. There was no evidence for complex formation. Metallothionein also failed to mobilize iron from ghosts of rabbit reticulocytes specifically labeled with59Fe.