"Interneurons" in the olfactory bulb revisited
"Interneurons" in the olfactory bulb revisited
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DOI：
10.1016/j.neures.2010.10.002
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发表时间：
2011-02-01
影响因子：
2.9
通讯作者：
Kosaka, Katsuko
中科院分区：
文献类型：
--
作者：
Kosaka, Toshio;Kosaka, Katsuko
主嗅球（MOBS）现在是大脑中最有趣的部分之一，至少在两个点上：嗅觉的第一站，作为理解感觉信息处理的神经机制的一个很好的模型和最突出的网站之一，其中间神经元在出生后和成年期不断产生。在这里，我们指出MOB组织的一些新方面，重点关注以下4个问题：（1）肾小球周围细胞中既有轴突细胞，也有无轴突细胞（PG细胞），（2）大多数小白蛋白阳性的中-外丛状层中的10 ~ 20 μ m大小的神经元以及少量一氧化氮合酶阳性的PG细胞和calretinin阳性的颗粒细胞是轴突型的，但显示出具有轴突特征的树突热点（4）酪氨酸羟化酶阳性GABA能神经元（tyrosine hydroxylase positive GABA Aergic neurons，简称DA-GABA能神经元）是一种特殊类型的JG神经元，是球间联系的主要来源，形成球内联合系统。(C)2010年爱思唯尔爱尔兰有限公司和日本神经科学学会。All rights reserved.
The main olfactory bulbs (MOBS) are now one of the most interesting parts of the brain in at least two points; the first station of the olfaction as an excellent model for understanding the neural mechanisms of sensory information processing and one of the most prominent sites whose interneurons are generated continuously in the postnatal and adult periods. Here we point out some new aspects of the MOB organization focusing on the following 4 issues: (1) there might be both axon-bearing and anaxonic periglomerular cells (PG cells), (2) most parvalbumin positive medium-sized neurons in the external plexiform layer as well as a few nitric oxide synthase positive PG cells and calretinin positive granule cells are anaxonic but display dendritic hot spots with characteristics of axon initial segments, (3) some of so-called "short-axon cells" project to the higher olfactory related regions and thus should be regarded as "nonprincipal projection neurons" and (4) tyrosine hydroxylase positive GABAergic (DA-GABAergic) juxtaglomerular neurons (JG neurons) are a particular type of JG neurons as a main source of the interglomerular connection, forming an intrabulbar association system. (C) 2010 Elsevier Ireland Ltd and the japan Neuroscience Society. All rights reserved.