Entering the era of single-cell transcriptomics in biology and medicine
Entering the era of single-cell transcriptomics in biology and medicine
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DOI：
10.1038/nmeth.2764
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发表时间：
2014-01-01
期刊：
影响因子：
48
通讯作者：
Sandberg, Rickard
中科院分区：
文献类型：
--
作者：
Sandberg, Rickard
最近的技术进步使单细胞中的RNA测序（RNA-seq）成为可能。探索性研究已经使我们深入了解了分化的动力学、细胞对刺激的反应以及转录的随机性。我们正在进入一个单细胞转录组学的时代，它有望对生物学和医学产生重大影响。
Recent technical advances have enabled RNA sequencing (RNA-seq) in single cells. Exploratory studies have already led to insights into the dynamics of differentiation, cellular responses to stimulation and the stochastic nature of transcription. We are entering an era of single-cell transcriptomics that holds promise to substantially impact biology and medicine.