Analysis of causal models of diet for patients with head and neck cancer receiving radiation therapy.
Analysis of causal models of diet for patients with head and neck cancer receiving radiation therapy.
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接受放射治疗的头颈癌患者饮食因果模型分析。
DOI：
10.1016/j.ejon.2010.05.003
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发表时间：
2010
期刊：
影响因子：
--
通讯作者：
Y. Shimizu
中科院分区：
文献类型：
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作者：
Norimasa Ogama;Sumie Suzuki;Y. Yasui;Katumi Azenishi;Y. Shimizu
本研究旨在建立维持接受放射治疗的头颈部癌症患者食欲的因果模型。SAMPLE和方法我们收集了208名接受30/50 GY两种剂量辐射的患者的食欲数据，并使用结构方程模型对数据进行了分析。结果在30 GY的因果模型中，我们建立了一条路径，使用了四个中介变量：平滑形式的食物的消费简易性，咀嚼质地和合适的温度的食物的简易性，味道鲜美的调味食物的简易性，从“饮食偏好”和“保持食欲，同时照顾口腔”之间的时间关系来看，“吃一顿饭的总体舒适度”。在50Gy射线的因果模型中，我们使用四个中间变量建立了一条路径，介于“容易食用温和温度和气味的食物”和“在照顾口腔的同时保持食欲”之间，使用四个中间变量“易于食用容易吞咽的食物”、“易于食用在口腔中溶解的食物”、“易于食用味道温和的食物”和“总体易于食用给定的一餐”。两种模型的拟合优度指数(GFI)和调整后的GFI(AGFI)均大于0.85，逼近均方误差(RMSEA)均小于0.08，具有较好的拟合优度。结论食物特性有助于维持30/50Gy射线累积剂量下患者的食欲。
PURPOSEThis study seeks to establish causal models of diet which maintain the appetites of head and neck cancer patients receiving radiation therapy.SAMPLE AND METHODSWe collected data from 208 patients at two radiation doses, 30/50 Gy, using a questionnaire on appetite and analyzed the items using structural equation modeling.RESULTSIn the causal model for 30 Gy, we established a path using the four intervening variables “ease of consuming foods in smooth forms,” “ease of consuming foods with a chewable texture and suitable temperature,” “ease of consuming lightly seasoned foods with a flavorful smell,” and “overall ease of consuming a given meal” from the temporal relationship between “dietary preferences” and “maintaining appetite while caring for the oral cavity.” In the causal model for 50 Gy, we established a path between “ease of consuming foods with a mild temperature and smell,” and “maintaining appetite while caring for the oral cavity” using the four intervening variables “ease of consuming foods that are easy to swallow,” “ease of consuming foods that dissolve well in the mouth,” “ease of consuming foods with a mild taste,” and “overall ease of consuming a given meal.” The goodness of fit indices for both models were above 0.85 for both the goodness of fit index (GFI) and adjusted GFI (AGFI), and less than 0.08 for root mean square error of approximation (RMSEA), indicating a satisfactory goodness of fit.CONCLUSIONSFood characteristics help to maintain patient appetite at cumulative radiation doses of 30/50 Gy.