Sclerosing carcinoma of the major intrahepatic bile ducts.

Sclerosing carcinoma of the major intrahepatic bile ducts.
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主要肝内胆管的硬化性癌。

DOI:
10.1001/archsurg.1957.01280150140015
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发表时间:
1957
期刊:
A.M.A. archives of surgery
影响因子:
--
通讯作者:
P. Hoxworth
P. Hoxworth
中科院分区:
--
文献类型:
--
作者:
W. Altemeier;E. Gall;M. M. Zinninger;P. Hoxworth

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原发性胆管癌可能起源于肝外或肝内。更常见的肝外型的临床和诊断特征是众所周知的,但肝内型的信息相当少。1-5发生于肝内胆管树较细根的粘膜细胞的癌被称为胆管瘤,通常被认为是肝脏原发性肿瘤的一种罕见形式。6.还有一种少见的原发性肝内胆管癌,这种癌比较少见,也比较难辨认。这种形式起源于肝门附近的主要肝内导管。其隐匿性、易于模仿其他胆道疾病以及相对难以手术入路等因素使得诊断非常困难,通常在尸检前无法诊断。2-4自1950年以来,三例原发性肝内胆管腺癌患者,
Primary carcinoma of the bile ducts may be extrahepatic or intrahepatic in origin. The clinical and diagnostic features of the more prevalent extrahepatic forms are well known, but considerably less information is available for the intrahepatic variety. 1-5 Carcinomas arising from the mucosal cells of the finer radicles of the intrahepatic biliary tree are known as cholangiomas and are usually considered to be an uncommon form of primary neoplasm of the liver. 6 There is another unusual type of primary carcinoma of the intrahepatic ducts which is rarer and more difficult to recognize. This form arises from the major intrahepatic ducts near the hilus. Its insidious nature, the ease with which it mimics other biliary tract disorders, and its relative inaccessibility to surgical approach are factors which have made diagnosis very difficult, and frequently impossible until autopsy. 2-4 Since 1950, three patients with primary adenocarcinoma of the intrahepatic bile ducts have