Expression profile analysis of microRNAs and downregulated miR-486-5p and miR-30a-5p in non-small cell lung cancer
Expression profile analysis of microRNAs and downregulated miR-486-5p and miR-30a-5p in non-small cell lung cancer
复制标题
非小细胞肺癌中 microRNA 及下调 miR-486-5p 和 miR-30a-5p 的表达谱分析。
DOI：
10.3892/or.2015.4141
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发表时间：
2015-10-01
期刊：
影响因子：
4.2
通讯作者：
Huang, Jian-An
中科院分区：
文献类型：
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作者：
Zhu, Jianjie;Zeng, Yuanyuan;Huang, Jian-An
肺癌是世界范围内癌症相关死亡的主要原因，尽管治疗有所改善，但存活率很低。本研究的目的是研究microRNA（miRNA）对细胞通路的影响。采用miRNA芯片技术对肺癌组织中的miRNA进行分析。经鉴定，33个变化>2.0倍的miRNAs和FDR
Lung cancer is the leading cause of cancer-related mortality worldwide and although there have been improvements in treatment there is a low survival rate. The aim of the present study was to investigate the effect of microRNA (miRNA) on cell pathways. A miRNA microarray was used to profile miRNAs of lung cancer tissues. It was identified that 33 miRNAs with >2.0-fold change and FDR