High prevalence of hepatitis B virus among female sex workers in Nigeria

High prevalence of hepatitis B virus among female sex workers in Nigeria
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DOI:
10.1590/s0036-46652008000400006
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发表时间:
2008-08-01
期刊:
Revista do Instituto de Medicina Tropical de São Paulo
影响因子:
--
通讯作者:
Agwale, S. M.
Agwale, S. M.
中科院分区:
其他
文献类型:
--
作者:
Forbi, J. C.;Onyemauwa, N.;Agwale, S. M.

文献摘要

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乙型肝炎病毒(HBV)感染是尼日利亚的一种地方病,对公共卫生构成威胁。尼日利亚描述了许多专业群体中HBV感染的流行情况。然而,关于尼日利亚女性性工作者(FSW)中HBV感染的文献很少。尼日利亚的女性生殖器官未受到乙型肝炎病毒感染的预防性控制。本研究评估了乙型肝炎病毒在尼日利亚FSW中的传播程度。采用双抗体夹心ELISA法检测720例(n = 720) FSW(平均年龄26.7岁)乙型肝炎表面抗原(HBsAg)。FSW人群的总体HBV患病率为17.1%。年龄在31-35岁之间的女性(20.5%)和“初次性行为年龄”在10岁以下的女性(28%)受影响最大。这种疫苗可预防疾病的高流行率是不可接受的,因此,应认为值得为这一高危HBV库群接种疫苗。
Hepatitis B Virus (HBV) infection is endemic in Nigeria and Constitutes it public health menace. The prevalence of HBV infection in many professional groups has been described in Nigeria. However, literature on HBV infection among female sex workers (FSW) in Nigeria is scanty. FSW in Nigeria are not subjected to a preventive control of HBV infection. This Study assesses the extent of spread of HBV among FSW in Nigeria. Seven hundred and twenty (n = 720) FSW (mean age = 26.7 years) were tested for hepatitis B surface antigen (HBsAg) by a double antibody sandwich ELISA method. The overall HBV prevalence among the FSW was 17.1%. FSWs between the aces of 31-35 year (20.5%) and those with 'age-at-first-sex' below 10 year of age (28%) were most affected. This high prevalence of a vaccine preventable disease is unacceptable, therefore, vaccination of this high risk HBV reservoir group should be considered worthwhile.