ULTRASTRUCTURE OF AMERICAN FOULBROOD DISEASE PATHOGENESIS IN LARVAE OF WORKER HONEY BEE, APIS-MELLIFERA
ULTRASTRUCTURE OF AMERICAN FOULBROOD DISEASE PATHOGENESIS IN LARVAE OF WORKER HONEY BEE, APIS-MELLIFERA
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DOI：
10.1016/0022-2011(73)90113-4
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发表时间：
1973-01-01
影响因子：
3.4
通讯作者：
DAVIDSON, EW
中科院分区：
文献类型：
--
作者：
DAVIDSON, EW
利用电子显微镜观察了美国臭蜂病的发病过程，从易受感染的幼龄蜜蜂幼虫摄入芽孢杆菌幼虫到寄主死亡和病原体产孢。宿主周围营养膜与b的相互作用。描述了幼虫的营养物。吞噬作用被证明是病原体进入宿主中肠细胞的一种机制。在病原体和宿主中肠细胞最初的相互作用过程中，没有发现酶消化周围营养膜或宿主细胞微绒毛的证据，尽管宿主肠道细胞的最终裂解可能是酶活性的结果。细菌进入血液后，宿主因全身性菌血症而死亡。
Using electron microscopy, the pathogenesis of American foulbrood disease was followed from ingestion ofBacillus larvaespores by young, susceptible honey bee larvae to death of the host and sporulation of the pathogen. Interaction between the host peritrophic membrane andB. larvaevegetatives is described. Phagocytosis was demonstrated to be a mechanism of entry of pathogen into host midgut cells. No evidence of enzymatic digestion of peritrophic membrane or host-cell microvilli was found during the initial interaction of pathogen and host midgut cell, although eventual lysis of host gut cells may have been the result of enzymatic activity. Following entry of bacteria into the hemocoel, host death resulted from systemic bacteremia.