Primary malignant lymphomas localized in salivary glands
Primary malignant lymphomas localized in salivary glands
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位于唾液腺的原发性恶性淋巴瘤
DOI：
10.1111/j.1365-2559.1982.tb02763.x
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发表时间：
1982
期刊：
影响因子：
6.4
通讯作者：
K. Lennert
中科院分区：
文献类型：
--
作者：
U. Schmid;D. Helbron;K. Lennert
本文对25例涎腺原发性恶性淋巴瘤进行了病理形态学观察和临床分析。不包括肌上皮性涎腺炎或干燥综合征的病例。21例肿瘤位于腮腺区，4例位于颌下区。21例活检诊断为非霍奇金淋巴瘤，4例诊断为霍奇金病：所有患者均为I期或II期。最常见的恶性淋巴瘤类型是中心母细胞-中心细胞型;在这15例病例中，除1例外，均发现硬化。多形性免疫细胞瘤2例，中心母细胞性淋巴瘤2例，免疫母细胞性淋巴瘤2例。在8例患者中，淋巴瘤肯定起源于腺内淋巴结，在其他10例患者中，淋巴瘤可能已经发展在腺内淋巴结。在其他7例病例中，无法确定淋巴瘤的起源。预后相对较好。
Biopsies from 25 patients with primary malignant lymphoma in the salivary region were investigated morphologically and the clinical findings were analysed. Cases showing myoepithelial sialadenitis or Sjögren's syndrome were not included. The tumour was localized in the parotid region in 21 cases and to the submandibular region in four cases. Non‐Hodgkin's lymphoma was diagnosed on 21 biopsies and Hodgkin's disease on four: all patients were of stages I or II. The most frequent type of malignant lymphoma was the centroblastic‐centrocytic type; sclerosis was found in all but one of these 15 cases. Polymorphic immunocytoma was diagnosed in two cases, centroblastic lymphoma in two cases and immunoblastic lymphoma in two cases. In eight patients, the lymphomas definitely originated in intraglandular lymph nodes; in 10 other patients, the lymphomas might have developed in intraglandular lymph nodes. It was not possible to determine the origin of the lymphoma in the other seven cases. The prognosis was relatively favourable.
影响因子：
11.2
作者：
P. Carbone;H. Kaplan;K. Musshoff;D. Smithers;M. Tubiana
通讯作者：
P. Carbone;H. Kaplan;K. Musshoff;D. Smithers;M. Tubiana