Risk factors for prosthetic joint infection: Case-control study
Risk factors for prosthetic joint infection: Case-control study
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DOI：
10.1086/514991
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发表时间：
1998-11-01
影响因子：
11.8
通讯作者：
Osmon, DR
中科院分区：
文献类型：
--
作者：
Berbari, EF;Hanssen, AD;Osmon, DR
我们进行了配对病例对照研究，确定了假体关节感染发生的危险因素。5例为人工髋关节或膝关节感染患者。对照组为接受全髋关节或膝关节置换术且未发生假体关节感染的患者。多元Logistic回归模型表明，假体关节感染的危险因素是发生不涉及假体的手术部位感染(优势比[OR]，35.9；95%可信区间[CI]，8.3-154.6)，国家医院感染监测系统手术患者风险指数得分为1(OR，1.7；95%CI，1.2-2.3)或2(OR，3.9；95%CI，2.0-7.5)，存在恶性肿瘤(OR，3.1；95%可信区间1.3-7.2)，关节置换史(OR，2.0；95%可信区间1.4-3.0)。我们的研究结果表明，手术部位感染不涉及关节假体、NNIS系统手术患者风险指数评分为1或2、存在恶性肿瘤和关节置换病史与假体关节感染的风险增加相关。
We conducted a matched case-control study tea determine risk factors for the development of prosthetic joint infection. Cases were patients with prosthetic hip or knee joint infection. Controls were patients who underwent total hip or knee arthroplasty and did not develop prosthetic joint infection. A multiple logistic regression model indicated that risk factors for prosthetic joint infection were the development of a surgical site infection not involving the prosthesis (odds ratio [OR], 35.9; 95% confidence interval [CI], 8.3-154.6), a National Nosocomial Infections Surveillance (NNIS) System surgical patient risk index score of 1 (OR, 1.7; 95% CI, 1.2-2.3) or 2 (OR, 3.9; 95% CI, 2.0-7.5), the presence of a malignancy (OR, 3.1; 95% CI, 1.3-7.2)., and a history of joint arthroplasty (OR, 2.0; 95% CI, 1.4-3.0). Our findings suggest that a surgical site infection not involving the joint prosthesis, an NNIS System surgical patient risk index score of 1 or 2, the presence of a malignancy, and a history of a joint arthroplasty are associated with an increased risk of prosthetic joint infection.