RACIAL-DIFFERENCES IN ALDOSTERONE EXCRETION AND PLASMA-ALDOSTERONE CONCENTRATIONS IN CHILDREN
RACIAL-DIFFERENCES IN ALDOSTERONE EXCRETION AND PLASMA-ALDOSTERONE CONCENTRATIONS IN CHILDREN
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DOI：
10.1056/nejm198910263211703
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发表时间：
1989-10-26
影响因子：
158.5
通讯作者：
FINEBERG, NS
中科院分区：
文献类型：
--
作者：
PRATT, JH;JONES, JJ;FINEBERG, NS
黑人更有可能患有高血压，血浆肾素活性水平较低，通常比白人摄入更少的钾。黑人和白人是否分泌不同数量的醛固酮还不太清楚。我们通过测量夜间尿醛固酮排泄率间接估计了715名儿童的醛固酮分泌量，其中249名是黑人。膳食中钠和钾的摄入量是根据它们的排泄率来估算的。黑人儿童的平均(±.SE)醛固酮排泄率低于白人儿童(0.045.±.0.003比0.078.±0.004毫摩尔每公斤体重肌酸)；
Blacks are more likely to have hypertension, have lower levels of plasma renin activity, and typically consume less potassium than whites. Whether blacks and whites secrete different amounts of aldosterone is less clear. We estimated aldosterone secretion indirectly in 715 children, 249 of whom were black, by measuring their nocturnal rates of urinary excretion of aldosterone. Dietary sodium and potassium intakes were estimated from their excretion rates. The mean (.+-.SE) aldosterone-excretion rate was lower in the black children than in the white children (0.045.+-.0.003 vs. 0.078.+-.0.004 nmol per micromole of creatinine per kilogram of body weight; P