Stability of Middle East respiratory syndrome coronavirus (MERS-CoV) under different environmental conditions

Stability of Middle East respiratory syndrome coronavirus (MERS-CoV) under different environmental conditions
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DOI:
10.2807/1560-7917.es2013.18.38.20590
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发表时间:
2013-09-19
期刊:
影响因子:
19
通讯作者:
Munster, V. J.
Munster, V. J.
中科院分区:
医学2区
文献类型:
--
作者:
van Doremalen, N.;Bushmaker, T.;Munster, V. J.

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中东呼吸综合征冠状病毒(MERS-CoV)在20℃-40%相对湿度(RH)、30℃-30%相对湿度(RH)和30℃-80%相对湿度(RH)下进行稳定性测定。MERS冠状病毒在低温低湿条件下较为稳定,48h后仍可恢复。在MERS-CoV的雾化过程中,在20摄氏度-40%RH下没有观察到稳定性下降。这些数据表明,由于长期存在于环境中,MERS-CoV有可能通过接触或混合传播传播。
The stability of Middle East respiratory syndrome coronavirus (MERS-CoV) was determined at 20 degrees C - 40% relative humidity (RH); 30 degrees C - 30% RH and 30 degrees C - 80% RH. MERS-CoV was more stable at low temperature/low humidity conditions and could still be recovered after 48 hours. During aerosolisation of MERS-CoV, no decrease in stability was observed at 20 degrees C - 40% RH. These data suggest the potential of MERS-CoV to be transmitted via contact or fomite transmission due to prolonged environmental presence.