Impact of hybrid iterative reconstruction on unenhanced liver CT.
Impact of hybrid iterative reconstruction on unenhanced liver CT.
复制标题
混合迭代重建对平扫肝脏 CT 的影响。
DOI：
10.1259/bjr.20150670
复制
发表时间：
2017
期刊：
影响因子：
--
通讯作者：
H. Honda
中科院分区：
文献类型：
--
作者：
Masatoshi Kondo;A. Nishie;N. Fujita;K. Morita;T. Shirasaka;H. Arimura;Yasuhiko Nakamura;H. Honda
目的
阐明混合迭代重建（HIR）和滤波反投影（FBP）对非增强肝脏CT的影响。
方法
30例肝细胞癌（HCC）患者行平扫CT检查。使用FBP和弱（1级）、轻度（4级）和强（7级）HIR（iDose 4; Philips Medical Systems，Cleveland，OH）重建图像。使用双尾配对t检验比较四种重建方法之间的定量、HCC（每例中最大病灶）的衰减、肝实质（四个节段的平均值）和图像噪声（肝实质中衰减的标准差）。还使用Wilcoxon符号秩检验比较了定性、肝脏病变显著性和表征。
结果
高水平HIR的肝脏病变的衰减显著高于FBP（p = 0.0005）。所有三种HIR水平的肝实质衰减均显著低于FBP（所有比较中p ≤ 0.0002）。三个HIR水平中的每一个的图像噪声均显著小于FBP的图像噪声（任何比较中p <0.0001）。FBP和每个HIR水平之间的病变显著性和表征无显著差异（所有比较中p ≥ 0.0819）。
结论
虽然HIR和FBP之间肝脏病变和肝实质的衰减有显著差异，但HIR对病变的显著性和特征没有显著影响。知识进展：肝脏病变和肝实质的衰减在HIR和FBP图像之间存在显著差异。
OBJECTIVE
To clarify the impact of hybrid iterative reconstruction (HIR) and filtered back projection (FBP) on unenhanced liver CT.
METHODS
30 patients with hepatocellular carcinoma (HCC) underwent unenhanced CT. The images were reconstructed with FBP and weak (Level 1), mild (Level 4) and strong (Level 7) levels of HIR (iDose4; Philips Medical Systems, Cleveland, OH). Quantitatively, attenuations of the HCC (with the largest lesion in each case), hepatic parenchyma (the average of four segments) and image noise (standard deviation of the attenuations in hepatic parenchyma) were compared between the four kinds of reconstruction using the two-tailed paired t-test. Qualitatively, liver lesion conspicuity and characterization were also compared using the Wilcoxon signed-rank test.
RESULTS
Attenuation of the liver lesion with the strong level of HIR was significantly higher than that with FBP (p = 0.0005). Attenuations of hepatic parenchyma with all three HIR levels were significantly lower than that with FBP (p ≤ 0.0002 in all comparisons). Image noise with each of the three HIR levels was significantly smaller than that with FBP (p < 0.0001 in any comparison). There was no significant difference in lesion conspicuity and characterization between FBP and each HIR level (p ≥ 0.0819 in all comparisons).
CONCLUSION
Although attenuations of the liver lesion and hepatic parenchyma were significantly different between HIR and FBP, HIR had no significant effect on lesion conspicuity and characterization. Advances in knowledge: Attenuations of liver lesions and hepatic parenchyma differ significantly between HIR and FBP images.