Paradoxes in acupuncture research: strategies for moving forward.
Paradoxes in acupuncture research: strategies for moving forward.
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DOI：
10.1155/2011/180805
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发表时间：
2011
期刊：
影响因子：
--
通讯作者：
Hammerschlag R
中科院分区：
文献类型：
--
作者：
Langevin HM;Wayne PM;Macpherson H;Schnyer R;Milley RM;Napadow V;Lao L;Park J;Harris RE;Cohen M;Sherman KJ;Haramati A;Hammerschlag R
2007年11月，针灸研究学会（SAR）举办了一次国际研讨会，以纪念1997年NIH针灸共识发展会议10周年。研讨会的报告显示了针灸研究领域的相当成熟，但出现了两个挑衅性的悖论。首先，一些精心设计的临床试验报告说，真正的针灸是上级的常规护理，但并没有显着优于假针灸，研究结果显然与传统的理论不一致，关于穴位特异性。第二，尽管许多使用动物和人类实验模型的研究已经报道了作为针刺参数的函数而变化的生理效应（例如，刺激模式）这些参数在临床试验中影响治疗结果的程度尚不清楚。这份白色白皮书由SAR董事会合作撰写，确定了悖论背后的知识差距，并提出了通过转化研究解决这些问题的策略。我们建议，针灸治疗应研究（1）“自上而下”的多组件“整体系统”的干预措施和（2）“自下而上”的机制研究，重点是了解如何个别治疗组件相互作用，并转化为临床和生理结果。这样一种战略，包括疗效，有效性和定性措施的考虑，将加强针灸等复杂干预措施的证据基础。
In November 2007, the Society for Acupuncture Research (SAR) held an international symposium to mark the 10th anniversary of the 1997 NIH Consensus Development Conference on Acupuncture. The symposium presentations revealed the considerable maturation of the field of acupuncture research, yet two provocative paradoxes emerged. First, a number of well-designed clinical trials have reported that true acupuncture is superior to usual care, but does not significantly outperform sham acupuncture, findings apparently at odds with traditional theories regarding acupuncture point specificity. Second, although many studies using animal and human experimental models have reported physiological effects that vary as a function of needling parameters (e.g., mode of stimulation) the extent to which these parameters influence therapeutic outcomes in clinical trials is unclear. This White Paper, collaboratively written by the SAR Board of Directors, identifies gaps in knowledge underlying the paradoxes and proposes strategies for their resolution through translational research. We recommend that acupuncture treatments should be studied (1) “top down” as multi-component “whole-system” interventions and (2) “bottom up” as mechanistic studies that focus on understanding how individual treatment components interact and translate into clinical and physiological outcomes. Such a strategy, incorporating considerations of efficacy, effectiveness and qualitative measures, will strengthen the evidence base for such complex interventions as acupuncture.
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影响因子：
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作者：
Cherkin, Daniel C.;Sherman, Karen J.;Avins, Andrew L.;Erro, Janet H.;Ichikawa, Laura;Barlow, William E.;Delaney, Kristin;Hawkes, Rene;Hamilton, Luisa;Pressman, Alice;Khalsa, Partap S.;Deyo, Richard A.
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Deyo, Richard A.
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168.9
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Kaptchuk, TJ
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Hogeboom, CJ;Sherman, KJ;Cherkin, DC
通讯作者：
Cherkin, DC
影响因子：
3
作者：
Furlan, AD;van Tulder, M;Berman, B
通讯作者：
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