pO2, pH, and Redox Potential of Experimental Abscesses

pO2, pH, and Redox Potential of Experimental Abscesses
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实验脓肿的 pO2、pH 和氧化还原电位

DOI:
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发表时间:
1974
期刊:
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine
影响因子:
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通讯作者:
G. Mandell
G. Mandell
中科院分区:
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文献类型:
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作者:
R. C. Hays;G. Mandell

文献摘要

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Summary Abscesses were induced in rats by injection of turpentine or turpentine plus bacteria. Other abscesses were induced by subcutaneous nitrogen injections followed by bacteria. pO2 of the abscesses was diminished (mean 25.3 mm Hg, range 0-75 mm Hg), the pH was acid (mean 7.0, range 6.2-7.2), and the oxidation-reduction potential was lowered (mean +1 mV, range −20 to +40 mV). Since low pO2 interferes with PMN bactericidal activity, this may in part explain the frequent failure of undrained abscesses to resolve.