The gun4 gene is essential for cyanobacterial porphyrin metabolism
The gun4 gene is essential for cyanobacterial porphyrin metabolism
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gun4基因对于蓝藻卟啉代谢至关重要
DOI：
10.1016/j.febslet.2004.06.063
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发表时间：
2004
期刊：
影响因子：
3.5
通讯作者：
B. Grimm
中科院分区：
文献类型：
--
作者：
A. Wilde;Sandra Mikolajczyk;Ali E Alawady;H. Lokstein;B. Grimm
Ycf53是一个假想的叶绿体开放阅读框，与拟南芥核基因GUN4相似。在植物中，GUN4参与四吡咯的生物合成。我们证明了两种聚球藻中的一种。与GUN4相似的PCC6803ycf53基因在叶绿素(Chl)生物合成中的功能也很相似：蓝藻GUN 4突变细胞的Chl含量较低，积累了原卟啉IX，不仅镁螯合酶和铁络合酶活性较低。Gun4在集胞藻镁和铁卟啉生物合成分支中的可能作用。讨论了PCC6803协议。
Ycf53 is a hypothetical chloroplast open reading frame with similarity to the Arabidopsis nuclear gene GUN4. In plants, GUN4 is involved in tetrapyrrole biosynthesis. We demonstrate that one of the two Synechocystis sp. PCC 6803 ycf53 genes with similarity to GUN4 functions in chlorophyll (Chl) biosynthesis as well: cyanobacterial gun4 mutant cells exhibit lower Chl contents, accumulate protoporphyrin IX and show less activity not only of Mg chelatase but also of Fe chelatase. The possible role of Gun4 for the Mg as well as Fe porphyrin biosynthesis branches in Synechocystis sp. PCC 6803 is discussed.