Magnetoencephalography in pediatric epilepsy.
Magnetoencephalography in pediatric epilepsy.
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DOI：
10.3345/kjp.2013.56.10.431
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发表时间：
2013-10-01
影响因子：
--
通讯作者：
Hwang, Hee
中科院分区：
文献类型：
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作者：
Kim, Hunmin;Chung, Chun Kee;Hwang, Hee
脑磁图（Magnetoencephalography，MEG）记录大脑皮层神经元电活动产生的磁场。信号不会失真或衰减，并且是非接触式记录，即使超过一个小时也可以舒适地进行。它具有出色的时间分辨率，特别是当它与患者自己的大脑磁共振成像（磁源成像）相结合时。脑磁图和脑电图的数据不是互斥的，而是同时记录和一起解释的。脑磁图已被证明是有用的，在病灶和非病灶性癫痫手术中检测刺激区。它提供了有价值的和额外的信息，在癫痫手术中应切除的病变。癫痫手术的较好结果与MEG刺激区的定位有关。脑磁图在癫痫手术中的价值在于招募更多患者接受癫痫手术，并为手术规划提供关键信息。脑磁图皮层标测对年轻的儿科患者很有帮助，尤其是当致痫灶靠近功能区时。脑磁图也用于癫痫的基础和临床研究，而不是外科手术。脑磁图在癫痫的诊断、治疗和研究中具有重要的价值。
Magnetoencephalography (MEG) records the magnetic field generated by electrical activity of cortical neurons. The signal is not distorted or attenuated, and it is contactless recording that can be performed comfortably even for longer than an hour. It has excellent and decent temporal resolution, especially when it is combined with the patient's own brain magnetic resonance imaging (magnetic source imaging). Data of MEG and electroencephalography are not mutually exclusive and it is recorded simultaneously and interpreted together. MEG has been shown to be useful in detecting the irritative zone in both lesional and nonlesional epilepsy surgery. It has provided valuable and additive information regarding the lesion that should be resected in epilepsy surgery. Better outcomes in epilepsy surgery were related to the localization of the irritative zone with MEG. The value of MEG in epilepsy surgery is recruiting more patients to epilepsy surgery and providing critical information for surgical planning. MEG cortical mapping is helpful in younger pediatric patients, especially when the epileptogenic zone is close to the eloquent cortex. MEG is also used in both basic and clinical research of epilepsy other than surgery. MEG is a valuable diagnostic modality for diagnosis and treatment, as well as research in epilepsy.