Behavioral and Neural Mechanisms Underlying Cognitive Vulnerability Models of Depression
Behavioral and Neural Mechanisms Underlying Cognitive Vulnerability Models of Depression
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DOI：
10.1037/a0031417
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发表时间：
2013-09-01
影响因子：
3.5
通讯作者：
Pechtel, Pia
中科院分区：
文献类型：
--
作者：
Auerbach, Randy P.;Webb, Christian A.;Pechtel, Pia
重度抑郁症显著影响青年和成年人的发展轨迹，抑郁症的认知脆弱性模型有助于我们理解抑郁症的发病、维持和复发。到目前为止，大部分的研究集中在三个突出的理论：（a）贝克的抑郁症认知模型。(b)抑郁症的绝望理论，和（c）反应风格理论。虽然这些病因学模型提供了丰富的信息，如何以及为什么抑郁症的出现，很少有人知道这些认知脆弱性因素的行为和神经生物学机制。本文概述了与青年和成年人抑郁症有关的关键但选择性的认知脆弱性因素的神经相关性。而且。为今后的研究提供了建议，因为它涉及到病因和治疗。
Major depressive disorder significantly impacts the developmental trajectory of youth as well as adults, and cognitive vulnerability models of depression have contributed to our understanding of the onset, maintenance, and recurrence of depression. To date, the bulk of research has focused on three prominent theories: (a) Beck's cognitive model of depression. (b) hopelessness theory of depression, and (c) response styles theory. Although these etiological models have provided a wealth of information about how and why depression arises, less is known about the behavioral and neurobiological mechanisms that underlie these cognitive vulnerability factors. The article provides an overview of neural correlates for critical, but selective, cognitive vulnerability factors implicated in depression in youth and adults. Moreover. recommendations are provided for future research as it relates to etiology and treatment.