1-Lithio-1,3-dienes as useful building blocks in organic synthesis
1-Lithio-1,3-dienes as useful building blocks in organic synthesis
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DOI：
10.1351/pac-con-08-08-04
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发表时间：
2009-01
影响因子：
1.8
通讯作者：
Wen‐Xiong Zhang;Z. Xi
中科院分区：
文献类型：
--
作者：
Wen‐Xiong Zhang;Z. Xi
摘要简要综述了1-锂-1，3-二烯对C-O和C-N不饱和底物的分子间反应活性和分子内反应。结果表明，烯基锂部分和丁二烯骨架之间的分子内协同作用使1-锂-1，3-二烯类化合物在有机合成中具有独特的应用价值。结果表明，取代方式和丁二烯骨架上取代基的性质对反应路径有显著影响。
Abstract Both intermolecular reactivities toward C-O and C-N unsaturated substrates and intramolecular reactions of various 1-lithio-1,3-dienes are briefly summarized. Results reveal that intramolecular synergy between the alkenyllithium moiety and the butadienyl skeleton make 1-lithio-1,3-diene derivatives useful and unique as building blocks in organic synthesis. It is demonstrated that substitution patterns and the nature of the substituents on the butadienyl skeleton have remarkable effects on reaction pathways.