Log linear relationship between plasma arginine vasopressin and plasma osmolality.
Log linear relationship between plasma arginine vasopressin and plasma osmolality.
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血浆精氨酸加压素和血浆渗透压之间的对数线性关系。
DOI：
10.1152/ajpendo.1977.233.1.e37
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发表时间：
1977
期刊：
影响因子：
--
通讯作者：
D. Fisher
中科院分区：
文献类型：
--
作者：
R. Weitzman;D. Fisher
综合血浆精氨酸加压素浓度（IpAVP）的测定，通过合并的结果，每3分钟收集的单个样品在脱水，随机水合，和水负载的羊。AVP浓度的对数与血浆渗透压浓度呈线性关系。通过向水负荷和随机水合的绵羊推注20 g/100 ml NaCl来测试这种关系。两组IpAVP对数的升高除以血浆渗透压的升高相似（P> 0.5），并可叠加在稳态观察所得的回归线上。这些数据表明，AVP释放作为血浆渗透压的指数函数，而不是作为阈值现象。
The integrated plasma arginine vasopressin concentration (IpAVP) was determined by pooling the results of single samples collected every 3 min for 0.5 h in dehydrated, randomly hydrated, and water-loaded sheep. A linear relationship was observed between the log of the integrated AVP concentration and plasma osmolality. This relationship was tested by the bolus injection of 20 g/100 ml NaCl to both water-loaded and randomly hydrated sheep. The rise in the log of IpAVP divided by the rise in plasma osmolality was similar in both groups (P greater than 0.5) and was superimposable upon the regression line derived from steady-state observations. The data would suggest that AVP is released as an exponential function of plasma osmolality rather than as a threshold phenomenon.