CNS syndromes associated with antibodies against metabotropic receptors.
CNS syndromes associated with antibodies against metabotropic receptors.
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与抗代谢受体抗体相关的中枢神经系统综合征。
DOI：
10.1097/wco.0000000000000448
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发表时间：
2017
影响因子：
4.8
通讯作者：
Lancaster,Eric
中科院分区：
文献类型：
--
作者：
Lancaster,Eric
CNS代谢型受体抗体可能对其靶受体产生直接抑制作用，但证据比离子型谷氨酸受体自身抗体更有限。在未来，对这些患者的更好识别可能会带来更好的结果。了解这些疾病的分子机制可能会发现新的治疗策略。
CNS metabotropic receptor antibodies may exert direct inhibitory effects on their target receptors, but the evidence is more limited than with autoantibodies to ionotropic glutamate receptors. In the future, improved recognition of these patients may lead to better outcomes. Understanding the molecular mechanisms of the diseases may uncover novel treatment strategies.