Electroanalysis and biosensors.

Electroanalysis and biosensors.
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DOI:
10.1021/a1999905e
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发表时间:
1993-06
影响因子:
7.4
通讯作者:
Joseph Wang
Joseph Wang
中科院分区:
化学1区
文献类型:
--
作者:
Joseph Wang

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This review covers primarily the development of biosensors and electrochemical schemes of clinical significance during the years 1997 and 1998. The review is not a comprehensive coverage of these topics. I have attempted to select those references that offer significant clinical relevance. Much of the general activity in the areas of electroanalysis and sensors has been documented in recent fundamental reviews in this journal (E1, E2). The interest in developing small sensing devices for biomedical use is growing rapidly. The potential clinical applications of such devices are enormous, particularly when point-of-care and criticalcare testing are concerned. Recent innovations are expected to provide the necessary improvements in convenience, patient care, cost, and turnout time and to have a major impact on health care early in the 21st century. Over the past two years we have witnessed new trends, including the integration of sensors with miniaturized (micromachined) analyzers, genetic design of recognition elements, rapid growth of genosensors, ultrafast monitoring of dynamic events in microscopic environments (including single-cell systems), molecular-sized electrodes, and introduction of advanced sensing materials. These emerging fields, along with continued investigations of novel biocatalytic and affinity biosensors, based on electrochemical, optical, or piezoelectric transducers, will no doubt enhance the power of biosensors and electroanalysis in the clinical arena.