Non-O group 1 Vibrio cholerae gastroenteritis in the United States: clinical, epidemiologic, and laboratory characteristics of sporadic cases.
Non-O group 1 Vibrio cholerae gastroenteritis in the United States: clinical, epidemiologic, and laboratory characteristics of sporadic cases.
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美国非 O 1 族霍乱弧菌胃肠炎：散发病例的临床、流行病学和实验室特征。
DOI：
10.7326/0003-4819-94-5-656
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发表时间：
1981
影响因子：
39.2
通讯作者：
P. Blake
中科院分区：
文献类型：
--
作者：
J. Morris;R. Wilson;B. Davis;I. Wachsmuth;C. Riddle;H. G. Wathen;R. Pollard;P. Blake
1979年，通过向疾病控制中心提交的分离株，确定了14例非o组1霍乱弧菌肠胃炎散发病例。所有患者均有腹泻，13例腹部痉挛，10例发烧，3例呕吐；其中4例患者出现血性腹泻。五名患者在发病前曾离开美国。所有9例国内感染病例均为在发病72小时内食用生蚝的患者；在一项匹配的病例对照研究中，这些患者的疾病与食用生海鲜密切相关（p < 0.0001）。通过Y-1肾上腺细胞试验，只有一种分离物产生热不稳定毒素。所有分离株均对四环素、氯霉素、卡那霉素和头孢菌素敏感。
Fourteen sporadic cases of non-O group 1 Vibrio cholerae gastroenteritis were identified through isolates submitted to the Centers for Disease Control in 1979. All the ill persons had diarrhea, 13 had abdominal cramps, 10 had fever, and three had vomiting; in four cases the patients had bloody diarrhea. Five patients had traveled outside the United States before they became ill. All nine domestically acquired cases were in patients who had eaten raw oysters within 72 hours of onset of illness; in a matched case-control study, illness in these patients was strongly associated with eating raw seafood (p less than 0.0001). Only one isolate produced heat-labile toxin by a Y-1 adrenal cell assay. All isolates were susceptible to tetracycline, chloramphenicol, kanamycin, and cephalothin.