Mesenchymal Stem Cell Fate: Applying Biomaterials for Control of Stem Cell Behavior.
Mesenchymal Stem Cell Fate: Applying Biomaterials for Control of Stem Cell Behavior.
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DOI：
10.3389/fbioe.2016.00038
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发表时间：
2016
影响因子：
5.7
通讯作者：
Dalby MJ
中科院分区：
文献类型：
--
作者：
Anderson HJ;Sahoo JK;Ulijn RV;Dalby MJ
生物材料和组织工程应用的材料管道正在不断发展。具体地，在干细胞竞技场中使用设计的材料引起了极大的兴趣，因为材料可用于操纵细胞以提供对行为的控制。这是重要的，因为“工程”复杂性和随后的组织和器官体外生长的能力是组织工程师的关键目标。这篇综述将描述材料策略的性质，静态和动态，以及它们对间充质干细胞命运的影响。
The materials pipeline for biomaterials and tissue engineering applications is under continuous development. Specifically, there is great interest in the use of designed materials in the stem cell arena as materials can be used to manipulate the cells providing control of behavior. This is important as the ability to “engineer” complexity and subsequent in vitro growth of tissues and organs is a key objective for tissue engineers. This review will describe the nature of the materials strategies, both static and dynamic, and their influence specifically on mesenchymal stem cell fate.