GENETIC AND DEVELOPMENTAL ANALYSIS OF AN ACID DEOXYRIBONUCLEASE IN DROSPHILA-MELANOGASTER
GENETIC AND DEVELOPMENTAL ANALYSIS OF AN ACID DEOXYRIBONUCLEASE IN DROSPHILA-MELANOGASTER
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DOI：
10.1007/bf00484532
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发表时间：
1978-01-01
影响因子：
2.4
通讯作者：
MACINTYRE, R
中科院分区：
文献类型：
--
作者：
DETWILER, C;MACINTYRE, R
研究了在酸性pH条件下，EDTA存在下黑腹黑腹果蝇的脱氧核糖核酸酶(DNase-1)活性。该酶的基因座位于第3染色体右臂上的61.8。在细胞遗传学上，DNase-1定位在90C-2和90E之间的5-10条带内。这项分析利用了Lindsley等人的电泳变异体和Y-常染色体易位。(1972)。DNase-1存在于生命周期的各个阶段，父本基因组在受精后0-1h主动为胚胎贡献DNase-1。
A deoxyribonuclease (DNase-1) that is active at acid pH in the presence of EDTA was studied in D. melanogaster. The locus for the enzyme maps genetically to 61.8 on the right arm of the 3rd chromosome. Cytogenetically, DNase-1 was localized to within 5-10 bands between 90C-2 and 90E. This analysis utilizes both electrophoretic variants and the Y-autosome translocations of Lindsley et al. (1972). DNase-1 is present in all stages of the life cycle, and the paternal genome actively contributes DNase-1 to the embryo 0-1 h after fertilization.