RELEASE OF (OLIGO) PEPTIDYL-TRANSFER-RNA FROM RIBOSOMES BY ERYTHROMYCIN-A
RELEASE OF (OLIGO) PEPTIDYL-TRANSFER-RNA FROM RIBOSOMES BY ERYTHROMYCIN-A
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DOI：
10.1073/pnas.72.7.2649
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发表时间：
1975-01-01
影响因子：
11.1
通讯作者：
KAJI, A
中科院分区：
文献类型：
--
作者：
OTAKA, T;KAJI, A
红霉素A在体外多肽合成系统中释放肽基trna。这与我们的假设一致，即红霉素A通过阻止核糖体供体(D)位点的寡肽- trna的适当位置来抑制易位。
Erythromycin A released peptidyl-tRNA in the in vitro polypeptide synthesis system with bacterial components programmed by synthetic polynucleotide. This is consistent with our hypothesis that erythromycin A inhibits translocation by preventing proper situation of oligopeptidyl-tRNA in the donor (D) site on ribosomes.