Validation of the acetylene rebreathing method for measurement of cardiac output at rest and during high-intensity exercise.
Validation of the acetylene rebreathing method for measurement of cardiac output at rest and during high-intensity exercise.
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验证用于测量静息和高强度运动期间心输出量的乙炔再呼吸方法。
DOI：
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发表时间：
1997
期刊：
影响因子：
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通讯作者：
J. Steinacker
中科院分区：
文献类型：
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作者：
Y. Liu;E. Menold;A. Dullenkopf;S. Reissnecker;W. Lormes;M. Lehmann;J. Steinacker
在高强度运动期间使用乙炔再呼吸法估计心输出量（CO）可能受到乙炔再循环的影响，尚未得到验证。本研究的目的是验证乙炔再呼吸法测量CO在高强度运动中使用直接菲克法。采用直接Fick法和乙炔再呼吸法分别在安静时和运动时测定9名受试者最大摄氧量（VO2max）的25%、50%、75%和90%时的CO。乙炔重吸法测定的CO与做功率（r = 0.90，P < 0.01）和摄氧量（r = 0.94，P < 0.01）相关。两种方法测定CO的相关系数r = 0.91（P < 0.01）。有没有显着差异，在CO测量的每种方法在休息，以及在每个工作率。每种方法之间的CO差异更大，在较低的CO比在较高的CO。在90%的VO2max，由乙炔再呼吸测量的CO几乎相同的Fick方法测量。结果表明，乙炔重吸法测定CO不仅在安静时有效，而且在运动时也有效，尤其是在高强度运动时。
The use of the acetylene rebreathing method to estimate cardiac output (CO) during high-intensity exercise, which may be influenced by recirculation of acetylene, has not been validated. This study was designed to validate the acetylene rebreathing method to measure CO during high-intensity exercise using the direct Fick method. CO was measured at rest and during exercise at 25%, 50%, 75% and 90% of the nine subjects' maximum oxygen uptake (VO2max) by the direct Fick and acetylene rebreathing method. CO measured by the acetylene rebreathing method correlated with work rate (r = 0.90, P < 0.01) and with oxygen uptake (r = 0.94, P < 0.01). The correlation coefficient of CO between both methods was r = 0.91 (P < 0.01). There was no significant difference in CO measured by each method at rest as well as at each work rate. The difference in CO between each method was greater at lower CO than at higher CO. At 90% of VO2max, the CO measured by acetylene rebreathing was nearly identical to that measured by the Fick method. It can be concluded that acetylene rebreathing for measurement of CO is valid not only at rest but also during exercise, especially during high-intensity exercise.