Cold atmospheric plasma: Charged species and their interactions with cells and tissues
Cold atmospheric plasma: Charged species and their interactions with cells and tissues
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DOI：
10.1109/tps.2008.2001084
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发表时间：
2008-08-01
影响因子：
1.5
通讯作者：
Graves, David B.
中科院分区：
文献类型：
--
作者：
Stoffels, Eva;Sakiyama, Yukinori;Graves, David B.
低温大气等离子体（CAP）治疗活体组织已成为现代等离子体物理学和医学领域的热门课题。血浆能够灭活细菌和非炎症性组织修饰，这使其成为伤口愈合和治疗皮肤病和龋齿的有吸引力的工具。关于血浆对细菌和哺乳动物细胞和组织的作用机制，从生物学和物理学的角度来看，仍有许多悬而未决的问题。例如，CAP的化学性质和各种血浆成分在组织治疗中的确切作用尚未完全解决。在本文中，我们将集中讨论等离子体中的带电物质（电子和离子）。讨论了典型大气等离子体源的物理特性；实验将面临的理论考虑，和几个生物医学方面的CAP治疗将进行调查。
Cold atmospheric plasma (CAP) treatment of living tissues becomes a popular topic in modern plasma physics and in medical sciences. The plasma is capable of bacterial inactivation and noninflammatory tissue modification, which makes it an attractive tool for wound healing and the treatment of skin diseases and dental caries. There are still many open issues with regard to the mechanisms of action of the plasma on bacteria and mammalian cells and tissues, both from the biological and the physical perspective. For example, the chemistry of CAP and the exact roles of various plasma constituents in tissue treatment are not yet fully resolved. In this paper, we shall concentrate on the charged species (electrons and ions) in the plasma. The selected physical properties of typical atmospheric plasma sources will be discussed; experiments will be confronted with theoretical considerations, and several biomedical aspects of CAP treatment will be surveyed.